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The activity "Finding Your Footing in the Shifting Landscape of Multiple Sclerosis" is currently unavailable.
Please refer to the Educational Activities Menu for a complete list of available offerings.
The educational activity, Finding Your Footing in the Shifting Landscape of Multiple Sclerosis, is available on 1/13/2021.
Please save-the-date! We look forward to your attendance.
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How confident are you in your knowledge of immunological mechanisms that contribute to MS?
How confident are you in your knowledge of clinical efficacy and safety of novel immune-dire?
How confident are you in your ability to assess disease progression in patients with MS?
Within an active MS lesion, which type of cell produces antibodies that bind to myelin?
In the CLARITY trial, what was the mean decrease in adjusted annualized relapse rate in patients receiving cladribine vs placebo?
In the SUNBEAM and RADIANCE clinical trials, what was the mean decrease in adjusted annualized relapse rate in patients receiving ozanimod versus interferon-beta 1a?
Lorene is a 35-year-old right-handed woman of Hispanic ethnicity who developed subacute weakness in her right hand along with an electrical sensation in her spine upon flexing her neck. MRI of brain and spinal cord showed 5 supratentorial and one posterior C2 hyperintensities, suggestive of demyelination.
Lumbar puncture (LP) showed: 9 CSF-restricted oligoclonal bands (OCBs), IgG Index 1.08 (high), normal glucose, sl high protein at 45. Six nucleated cells (no diff), 0 red blood cells (RBCs).
Lorene works as a clerk in a department store, and her main complaints are fatigue, and right-hand clumsiness, which is intermittently worse and better. She was diagnosed with RRMS and began interferon beta-1b given every other day subcutaneously. She continued to take beta-interferon for 2 years, adherently, despite continued flu-like symptoms but without any clinical worsening or relapses.
She underwent her yearly surveillance MRI which showed a single enhancing juxtacortical lesion, which was asymptomatic, in addition to her already-known brain and spinal cord lesions which were unchanged. She denies missing any doses of subcutaneous beta-interferon therapy.
Which is least likely to be an effective strategy for treating Lorene at this point?
TV-123-011321-90 PRE-TEST
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Finding Your Footing in the Shifting Landscape of Multiple Sclerosis
Live Symposium 1/13/2021 - 1/13/2022
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