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Weight Gain with the Atypicals: How to Screen, Monitor, and Intervene

neuroscienceCME TV

Premiere Date: Wednesday, March 21, 2007

This activity offers CE credit for:

1. Physicians (ACCME/AMA PRA Category 1)
2. Nurses (CNE)
3. Pharmacists (ACPE)
4. Psychologists (APA)
5. Social Workers (NASW)
6. Certified Case Managers (CCMC)

All other clinicians will receive a Certificate of Attendance stating this activity was certified for AMA PRA Category 1 Credit™

Credit Expiration Date:
Friday, March 21, 2008
Note: Credit Is No Longer Available

Faculty

Charles B. Nemeroff, MD, PhD  Professor and Chair Department of Psychiatry Mulva Clinic for the Neurosciences Director, Institute of Early Life Adversity Research Dell Medical School The University of Texas at Austin Austin, TX

Robert R. Conley, MD  Distinguished Scholar, Eli Lilly and Company Adjunct Professor of Psychiatry and Pharmacy Science University of Maryland, Baltimore Baltimore, MD

John W. Newcomer, MD  Senior Associate Dean for Clinical Research Leonard M. Miller Professor of Psychiatry and Behavioral Sciences Leonard M. Miller School of Medicine University of Miami Miami, FL

Statement of Need

Obesity is reaching epidemic proportions in the United States. Its prevalence in U.S. adults doubled between 1980 and 2002,(1) and a recent report indicates that the obesity rate in 2003-2004 reached 32.2%.(2) Patients with serious mental health issues such as schizophrenia and bipolar disorder are prone to concomitant metabolic problems, such as metabolic syndrome, diabetes, and obesity.(3) In the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) trial, more than one-third of males and one-half of all females fit the metabolic syndrome criteria,(4) as defined by Adult Treatment Panel III (ATP III).(5) Physicians treating patients with schizophrenia need to be aware of the impact of overweight and obesity on their patients’ wellness and how they can screen, monitor, and intervene to address this healthcare crisis. At the Summer 2006 Commissioners Meeting of the National Association of State Mental Health Program Directors, the medical directors recommended that healthcare providers 1) screen for general health with priority for high-risk conditions (e.g., diabetes, cardiovascular disease), 2) screen, monitor, and intervene for medication-related risk factors, such as risk of metabolic syndrome with use of atypical antipsychotics, and 3) provide treatment per practice guidelines. In this live and interactive, evidence-based neuroscienceCME TV activity, the experts will explore the challenges clinicians face when managing weight gain associated with atypical antipsychotics, and develop strategies to screen, monitor, and intervene to improve outcomes in their patients with schizophrenia.

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1. Flegal KM, Carroll MD, Ogden CL, Johnson CL. Prevalence and trends in obesity among US adults, 1999-2000. JAMA 2002;288:1723-1727.
2. Ogden CL, Carroll MD, Curtin LR, McDowell MA, Tabak CJ, Flegal KM. Prevalence of overweight and obesity in the United States 1999-2004. JAMA 2006;295:1549-1555.
3. Cohen D, Stolk RP, Grobbee DE, Gispen-DeWied CC. Hyperglycemia and diabetes in patients with schizophrenia or schizoaffective disorders. Diabetes Care 2006;29:786-791.
4. Lieberman JA, Stroup TS, McEvoy JP, et al. Effectiveness of antipsychotic drugs in patients with chronic schizophrenia. N Engl J Med 2005;353:1209-23. Epub 2005 Sep 19.
5. Detection, Evaluation, and Treatment of high blood cholesterol in adults (Adult Treatment Panel III). U.S. Dept of Health and Human Services, May 2001. NIH Publication #01-3670.

Activity Goal

To recognize the impact of weight gain associated with atypical antipsychotics and develop strategies to screen, monitor, and intervene to improve outcomes in patients with schizophrenia.

Learning Objectives

At the end of this CE activity, participants should be able to:

• Apply recent guidelines to improve clinical skills in screening, monitoring, and intervention in patients with schizophrenia at risk for metabolic disorders.
• Employ proper technique for measuring waist circumference and translating the measurement into cardiovascular risk.
• Recognize the metabolic impact associated with choice of agent, duration of trial, and pharmacokinetic issues (metabolites, bioavailability) of antipsychotic agents to minimize risk from weight gain in patients with schizophrenia.

Target Audience

Physicians, physician assistants, nurse practitioners, nurses, psychologists, social workers, certified case managers, pharmacists, and other healthcare professionals with an interest in mental health.

Credit Information

CME Credit (Physicians):
CME Outfitters, LLC, is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. CME Outfitters, LLC, designates this educational activity for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

CNE Credit (Nurses):
CME Outfitters, LLC, is an approved provider of continuing nursing education by the New York State Nurses Association, an accredited approver by the American Nurses Credentialing Center’s Commission on Accreditation.

It has been assigned code 6WASUP-PRV-062. 1.0 contact hours will be awarded upon successful completion.
Note to Nurse Practitioners: The content of this CNE activity pertains to Pharmacology.

CEP Credit (Psychologists):
CME Outfitters is approved by the American Psychological Association to sponsor continuing education for psychologists. CME Outfitters maintains responsibility for this program and its content. (1.0 CE credits)

NASW Credit (Social Workers):
This program was approved by the National Association of Social Workers (provider #886407722) for 1 continuing education contact hour.

CCMC Credit (Certified Case Managers):
This program has been approved for 1 hour by the Commission for Case Manager Certification (CCMC).

CPE Credit (Pharmacists):
CME Outfitters, LLC, is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education. 1.0 contact hours (0.1 CEUs)
Universal Program Number: 376-999-07-002-L01 (live presentation) 376-999-06-002-H01 (recorded programs)

To receive credit, participants must review all activity materials in their entirety, score 70% or above on a post-test, and fully complete and return both the credit request form and activity evaluation. A certificate or statement of credit will be mailed within 4-6 weeks to all who successfully complete these requirements.

Disclosure Declaration

All faculty participating in CME Outfitters continuing education activities are required to disclose any conflict(s) of interest related to the content of their presentation(s) as defined by the ACCME's Standards for Commercial Support, and other accrediting and regulatory bodies. Full disclosure of faculty relationships will be made on this website and within the activity course materials prior to the premiere date of this activity.

Questions about this activity? Call us at 877.CME.PROS (877.263.7767).