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Matching Treatment Choice to the Pathophysiology of Sleep

Premiere Date: Thursday, October 29, 2020

This activity offers CE credit for:

  1. Physicians (CME)
  2. Pharmacists (ACPE)
  3. ABIM (MOC)
  4. ABP (MOC)
  5. Other


All other clinicians will receive a Certificate of Attendance stating this activity was certified for AMA PRA Category 1 Credit™

Credit Expiration Date:
Friday, December 31, 2021
Note: Credit Is No Longer Available

Faculty


Richard K. Bogan, MD, FCCP, FAASMRichard K. Bogan, MD, FCCP, FAASM 
Associate Clinical Professor
University of South Carolina Medical School, Columbia, SC
Medical University of South Carolina, Charleston, SC
Principal, Bogan Sleep Consultants, LLC
Charleston, SC

Yves Dauvilliers, MD, PhDYves Dauvilliers, MD, PhD 
Professor of Neurology and Physiology
University of Montpellier
Director, Sleep-Wake Disorders Centre
Department of Neurology
Gui de Chauliac Hospital
Montpellier, France

Statement of Need

The neurobiology of excessive daytime sleepiness (EDS) in obstructive sleep apnea (OSA) has no identified pathophysiology. This can make it difficult for clinicians to determine a target for therapeutic intervention; therefore, awareness of the mechanisms of action of current and novel therapies is vital when selecting an optimal treatment.

In the second episode of this CME Outfitters podcast series on EDS, expert faculty will focus on identifying key neurotransmitters involved in the sleep-wake cycle and recognizing how therapies targeted to those key neurotransmitters exert their therapeutic effect on EDS in narcolepsy and OSA.

Learning Objectives

At the end of this CE activity, participants should be able to:

  • Evaluate the significance of mechanism of action when selecting optimal treatment of EDS in patients with OSA or narcolepsy.

The following learning objectives pertain only to those requesting CNE or CPE credit:

  • Explain the significance of mechanism of action for selecting optimal treatment of EDS in patients with OSA or narcolepsy.

Financial Support

Supported by an educational grant from Jazz Pharmaceuticals, Inc.

Target Audience

Sleep specialists, pulmonologists, neurologists, psychiatrists, primary care physicians, pediatricians, PAs, nurse practitioners, and pharmacists

Credit Information

CME Credit (Physicians):
CME Outfitters, LLC, is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

CME Outfitters, LLC, designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

CPE Credit (Pharmacists):
ACPE CME Outfitters, LLC, is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education. 0.25 contact hours (0.025 CEUs) Universal Activity Number:
Enduring: 0376-0000-20-116-H01-P

Type: Knowledge-based

ABIM/MOC Credit:
Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to .25 MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.
Learning Format:
Enduring activity

ABP MOC Credit:
Successful completion of this CME activity, which includes participation in the activity and individual assessment of and feedback to the learner, enables the learner to earn up to .25 MOC points in the American Board of Pediatrics' (ABP) Maintenance of Certification (MOC) program. It is the CME activity provider's responsibility to submit learner completion information to ACCME for the purpose of granting ABP MOC credit.

Royal College MOC:
Through an agreement between the Accreditation council for Continuing Medical Education and the Royal College of Physicians and Surgeons of Canada, medical practitioners participating in the Royal College MOC Program may record completion of accredited activities registered under the ACCME's "CME in Support of MOC" program in Section 3 of the Royal College's MOC Program.

MIPS Improvement Activity: This activity counts towards MIPS Improvement Activity requirements under the Medicare Access and CHIP Reauthorization Act of 2015 (MACRA). Clinicians should submit their improvement activities by attestation via the CMS Quality Payment Program website.

Note to PAs: PAs may claim a maximum of .25 Category 1 credits for completing this activity. NCCPA accepts AMA PRA Category 1 Credit™ from organizations accredited by ACCME or a recognized state medical society.

Note to Nurse Practitioners: Nurse Practitioners can apply for AMA PRA Category 1 Credit™ through the American Academy of Nurse Practitioners (AANP). AANP will accept AMA PRA Category 1 Credit™ from organizations accredited by the Accreditation Council for Continuing Medical Education. Nurse practitioners can also apply for credit through their state boards.

ABPN Diplomates may select any CME activity relevant to their practice to count towards ABPN MOC requirements.

Post-tests, credit request forms, and activity evaluations must be completed online (requires free account activation), and participants can print their certificate or statement of credit immediately (75% pass rate required). This website supports all browsers except Internet Explorer for Mac. For complete technical requirements and privacy policy, visit www.cmeoutfitters.com/technical.asp.

Disclosure Declaration

It is the policy of CME Outfitters, LLC, to ensure independence, balance, objectivity, and scientific rigor and integrity in all of their CE activities. Faculty must disclose to the participants any relationships with commercial companies whose products or devices may be mentioned in faculty presentations, or with the commercial supporter of this CE activity. CME Outfitters, LLC, has evaluated, identified, and attempted to resolve any potential conflicts of interest through a rigorous content validation procedure, use of evidence-based data/research, and a multidisciplinary peer review process. The following information is for participant information only. It is not assumed that these relationships will have a negative impact on the presentations.

Dr. Bogan reports that he is a consultant for Harmony Biosciences, LLC; and Jazz Pharmaceuticals, Inc. He takes part in industry funded research with Avadel/Flamel Ireland LTD; Axsome Therapeutics, Inc.; Balance; Eisai Inc.; Fresca; Jazz Pharmaceuticals, Inc.; and Merck & Co., Inc. He is on the speakers bureau for Jazz Pharmaceuticals, Inc.; and Merck & Co., Inc. He is a shareholder, on the Board of Directors, the Chief Medical Officer, and an employee of SleepMed, Inc. He receives other financial or material support as a member of the Board of Directors for First Community Corporation, SC; and National Sleep Foundation.

Dr. Dauvilliers reports that he receives grants from Jazz Pharmaceuticals, Inc. He receives research support from Bioprojet; Idorsia Pharmaceuticals Ltd; Jazz Pharmaceuticals, Inc.; Takeda Pharmaceutical Company Limited; and UCB S.A., Belgium. He is on the advisory committee for Bioprojet; Idorsia Pharmaceuticals Ltd; Jazz Pharmaceuticals, Inc.; Takeda Pharmaceutical Company Limited; and UCB S.A., Belgium. He is a consultant for Bioprojet; Idorsia Pharmaceuticals Ltd; Jazz Pharmaceuticals, Inc.; Takeda Pharmaceutical Company Limited; and UCB S.A., Belgium.

Tony Graham, MD (peer reviewer) has no disclosures to report.

Mae Ochoa, RPh (peer reviewer) has no disclosures to report.

Kashemi D. Rorie, PhD (planning committee) has no disclosures to report.

Evan Luberger (planning committee) has no disclosures to report.

Jan Perez (planning committee) has no disclosures to report.

Sharon Tordoff (planning committee) has no disclosures to report.

Disclosures were obtained from the CME Outfitters, LLC staff: No disclosures to report.

Faculty of this CE activity may include discussions of products or devices that are not currently labeled for use by the FDA. The faculty have been informed of their responsibility to disclose to the audience if they will be discussing off-label or investigational uses (any uses not approved by the FDA) of products or devices.

Questions about this activity? Call us at 877.CME.PROS (877.263.7767).

PD-032-102920-43

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