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Maintaining Momentum in the Treatment of Chronic Idiopathic Constipation: Framing Practical Clinical Strategies Through Case Studies

Premiere Date: Thursday, June 2, 2022

This activity offers CE credit for:

  1. ABIM (MOC)
  2. Medicine (accme)
  3. Nursing (ANCC)
  4. Pharmacy (acpe)
  5. PA (aapa)
  6. Other

All other clinicians will receive a Certificate of Attendance stating this activity was certified for AMA PRA Category 1 Credit™

Credit Expiration Date:
Friday, June 2, 2023
Note: Credit Is No Longer Available


Michael Camilleri, MDMichael Camilleri, MD (Moderator)
Atherton and Winifred Bean Professor of Medicine,
Pharmacology, and Physiology
Mayo Clinic
Rochester, MN

Dan and Lillie Sterling Professor of Clinical Gastroenterology
Chief, Division of Gastroenterology, Hepatology, and Nutrition
University of Texas Health Science Center at Houston
Houston, TX

Lucinda A. Harris, MS, MD, FACG, AGAF, FACPLucinda A. Harris, MS, MD, FACG, AGAF, FACP 
Associate Professor of Medicine
Consultant, Division of Gastroenterology and Hepatology
Mayo Clinic - Alix School of Medicine
Scottsdale, AZ

Statement of Need

Despite its prevalence, chronic idiopathic constipation (CIC) is often underdiagnosed, undertreated, and mismanaged, exacting a significant personal and economic burden for affected individuals. Overlapping symptoms with other functional gastrointestinal disorders complicate the diagnosis and treatment of CIC. There is a need for practical strategies in choosing and interpreting appropriate diagnostic tests, as well as a thorough understanding of safety and efficacy data in order to efficiently and effectively progress through the treatment continuum.

In this CME Outfitters OnDemand symposium, expert faculty will frame the CIC decision tree with patient cases in order to achieve a confident diagnosis, implement effective treatment plans to improve outcomes, and improve quality of life for patients with CIC.

Learning Objectives

At the end of this CE activity, participants should be able to:

  • Accurately diagnose CIC, differentiating it from IBS-C.
  • Evaluate the characteristics of therapies used in the management of CIC.
  • Develop a comprehensive treatment strategy for patients with CIC, constructed from evidence and clinical guidelines.

Financial Support

Supported by an educational grant from Takeda Pharmaceuticals U.S.A., Inc.

Target Audience

Physicians, PAs, nurse practitioners, nurses, and pharmacists specializing in gastroenterology and/or primary care

Credit Information

ABIM MOC Credit:
Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1.5 medical knowledge MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

Learning Formats
Enduring Material

Royal College MOC:
Through an agreement between the Accreditation Council for Continuing Medical Education and the Royal College of Physicians and Surgeons of Canada, medical practitioners participating in the Royal College MOC Program may record completion of accredited activities registered under the ACCME’s “CME in Support of MOC” program in Section 3 of the Royal College’s MOC Program.

MIPS Improvement Activity:
This activity counts towards MIPS Improvement Activity requirements under the Medicare Access and CHIP Reauthorization Act of 2015 (MACRA). Clinicians should submit their improvement activities by attestation via the CMS Quality Payment Program website.

Disclosure Declaration

It is the policy of CME Outfitters, LLC, to ensure independence, balance, objectivity, and scientific rigor and integrity in all of their CE activities. Faculty must disclose to the participants any relationships with commercial companies whose products or devices may be mentioned in faculty presentations, or with the commercial supporter of this CE activity. CME Outfitters, LLC, has evaluated, identified, and attempted to resolve any potential conflicts of interest through a rigorous content validation procedure, use of evidence-based data/research, and a multidisciplinary peer review process. The following information is for participant information only. It is not assumed that these relationships will have a negative impact on the presentations.

Dr. Camilleri reports the following financial relationships:

Consultant: Acadia Pharmaceuticals Inc.; Aditum Bio; AEON Biopharm; BioKier, Inc.; Colospan; Cosma Pharmaceuticals; Fauna Bio; Novome Biotechnologies, Inc.; Pfizer Inc.; Protagonist Therapeutics, Inc.; QED Therapeutics, Inc.; Sunovion Pharmaceuticals Inc.; and Zealand Pharma A/S

Grants: NGM Biopharmaceuticals and Vanda Pharmaceuticals

Other financial or material support: option to receive stock for consulting with Bilayer Therapeutics; Dignify Therapeutics; Enterin Inc.; and Thelium Therapeutics

Dr. Cash reports the following financial relationships:

Advisory Board: AbbVie Inc.; Phathom Pharmaceuticals; and Takeda Pharmaceuticals U.S.A., Inc.

Consultant: Alexion; Motus; Nestle; and Phathom Pharmaceuticals

Research Support: Napo Pharmaceuticals, Inc.

Speakers Bureau: AbbVie Inc.; Alnylam Pharmaceuticals, Inc; QOL Medical, LLC; RedHill Biopharma Ltd; Salix Pharmaceuticals; and Takeda Pharmaceuticals U.S.A., Inc.

Dr. Harris reports the following financial relationships:

Consultant: AbbVie (formerly Allergan); Alnylam Pharmaceuticals, Inc.; Gemelli Biotech; GI Health Foundation; Ironwood Pharmaceuticals, Inc.; Rome Foundation; Salix Pharmaceuticals; and Takeda Pharmaceuticals U.S.A., Inc. (formally Shire)

Research Support: Allakos Inc.

The following peer reviewer and CME Outfitters staff have no financial relationships:

  • Shirley Michelle Franks, MSN, APRN, FNP-BC (peer reviewer)
  • Susan Perry (planning committee)
  • Kasey Brandt, PharmD (planning committee)
  • Susan H. Yarbrough, CHCP (planning committee)
  • Sharon Tordoff (planning committee)

  • Faculty of this CE activity may include discussions of products or devices that are not currently labeled for use by the FDA. The faculty have been informed of their responsibility to disclose to the audience if they will be discussing off-label or investigational uses (any uses not approved by the FDA) of products or devices.

    Questions about this activity? Call us at 877.CME.PROS (877.263.7767).


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