Expert Guidance on Novel Approaches in the Management of MyelofibrosisPremiere Date: Wednesday, January 11, 2023
This activity offers CE credit for:%>
- ABIM (MOC)
- Medicine (accme)
- Nursing (ANCC)
- Pharmacy (acpe)
- PA (aapa)
All other clinicians will receive a Certificate of Attendance stating this activity was certified for AMA PRA Category 1 Credit™
Credit Expiration Date:
Thursday, January 11, 2024
|Ruben A. Mesa, MD, FACP (Moderator)
Executive Director, Mays Cancer Center at UT Health San Antonio MD Anderson
Mays Family Foundation Distinguished University Presidential Chair
Professor of Medicine UT Health San Antonio
San Antonio, TX
|Angela G. Fleischman, MD, PhD
Division of Hematology/Oncology
University of California, Irvine
|Aaron T. Gerds, MD, MS
Associate Professor of Medicine, Hematology & Medical Oncology
Deputy Director for Clinical Research Cleveland Clinic Taussig Cancer Institute
Medical Director, Case Comprehensive Cancer Center Clinical Research Office
Principal Investigator, Case Lead Academic Participating Site
Myelofibrosis (MF) is a rare bone marrow cancer characterized by severe anemia, weakness, fatigue, and other constitutional symptoms that can severely compromise quality of life (QoL). JAK/STAT pathway inhibition is the standard of care for patients with symptomatic MF. However, certain JAK inhibitors (JAKi) can exacerbate anemia and may be unsuitable for patients dependent on red blood cell (RBC) transfusions.
Other key signaling pathways are being explored to foster development of novel therapies that can overcome challenges associated with JAKis, but clinicians need guidance on these novel therapies in order to optimize clinical outcomes. This educational initiative will survey the expanding treatment options for patients with MF, including non-JAKi agents targeting non-canonical molecular pathways.
At the end of this CE activity, participants should be able to:
- Identify molecular and clinical features of MF that inform care plans.
- Evaluate novel and investigational therapies for the management of MF.
- Devise personalized strategies to integrate emerging evidence for MF.
This educational activity is supported by an educational grant from GSK.
Physicians, PAs, nurse practitioners, nurses, and pharmacists specializing in hematology or oncology.
Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1.0 medical knowledge MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.
Royal College MOC:
Through an agreement between the Accreditation Council for Continuing Medical Education and the Royal College of Physicians and Surgeons of Canada, medical practitioners participating in the Royal College MOC Program may record completion of accredited activities registered under the ACCME’s “CME in Support of MOC” program in Section 3 of the Royal College’s MOC Program.
MIPS Improvement Activity:
This activity counts towards MIPS Improvement Activity requirements under the Medicare Access and CHIP Reauthorization Act of 2015 (MACRA). Clinicians should submit their improvement activities by attestation via the CMS Quality Payment Program website.
Dr. Mesa reports the following financial relationships:
Consultant: AbbVie Inc.; Blueprint Medicines Corporation; Bristol Myers Squibb; CTI Biopharma Corp.; Genentech, Inc.; Geron; GSK; Incyte; Novartis Pharmaceuticals Corporation; Sierra Oncology, Inc.; and Telios pharmaceuticals
Editorial Advisory Board: Clinical Advances in Hematology & Oncology
Grants: Mays Cancer Center P30 Cancer Center Support Grant from National Cancer Institute (CA054174)
Research Support: AbbVie Inc.; Blueprint; Bristol Myers Squibb; CTI Biopharma Corp.; Genentech, Inc.; Incyte; MorphoSys; and Sierra Oncology, Inc.
The following CME Outfitters peer reviewer and staff have no financial relationships:
Dr. Fleischman reports the following financial relationships:
Advisory Board: Incyte; PharmaEssentia Corporation; and Sierra Pharma
Speakers Bureau: CTI Biopharma Corp. and PharmaEssentia Corporation
Dr. Gerds reports the following financial relationships:
Advisory Board: AbbVie Inc.; CTI Biopharma Corp.; MorphoSys; PharmaEssentia Corporation; and Sierra Oncology, Inc./GSK
Faculty of this CE activity may include discussions of products or devices that are not currently labeled for use by the FDA. The faculty have been informed of their responsibility to disclose to the audience if they will be discussing off-label or investigational uses (any uses not approved by the FDA) of products or devices.
Questions about this activity? Call us at 877.CME.PROS (877.263.7767).