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Novel Treatment of Inflammatory Bowel Disease Informed by Science and Patient Choice

Click Here To Download Faculty Response to Questions from the Live Webcast (PDF)

Premiere Date: Wednesday, March 11, 2015

This activity offers CE credit for:

  1. Physicians (CME)
  2. Nurses (CNE)
  3. Pharmacists (ACPE)
  4. Other


All other clinicians will receive a Certificate of Attendance stating this activity was certified for AMA PRA Category 1 Credit™

Credit Expiration Date:
Friday, March 11, 2016
Note: Credit Is No Longer Available

Faculty


Russell D. Cohen, MD, FACG, AGAFRussell D. Cohen, MD, FACG, AGAF 
Professor of Medicine, Pritzker School of Medicine
Director, Inflammatory Bowel Disease Center
Co-Director, Advanced IBD Fellowship Program
University of Chicago Medicine
Chicago, IL

Gary R. Lichtenstein, MD, FACP, FACG, AGAF Gary R. Lichtenstein, MD, FACP, FACG, AGAF  
Professor of Medicine
Raymond and Ruth Perelman School of Medicine
Director, Center for Inflammatory Bowel Disease
Department of Medicine
Division of Gastroenterololgy
University Of Pennsylvania
Philadelphia, PA

Miguel Regueiro, MD, FACP, FACG, AGAFMiguel Regueiro, MD, FACP, FACG, AGAF 
Professor of Medicine, Professor of Clinical and Translational Science
University of Pittsburgh School of Medicine
Associate Chief, Education
Division of Gastroenterology, Hepatology, and Nutrition
Clinical Medical Director of Inflmmatory Bowel Disease
Senior Medical Lead of Specialty Medical Homes
University of Pittsburgh Medical Center
Pittsburgh, PA

Statement of Need

Inflammatory bowel disease (IBD), which consists of Crohn’s disease (CD) and ulcerative colitis (UC), is a chronic inflammatory disease of the gut, which develops because of an excessive immune response to the normal gut flora in a genetically susceptible host.1 Current therapies for IBD have not, as yet, been able to prevent the need for surgical intervention in more than 50% of IBD patients. Education to clinicians who manage patients with moderate-to-severe IBD about the immunopathophysiology of IBD and the latest available options to individualize IBD treatment can reduce the use of corticosteroids and need for hospitalizations or surgery resulting in improved quality of life for these patients. Clinicians often treat IBD based only on diagnosis rather than considering an individual’s uniqueness, personal history, risk factors, genetics, possible immunopathogenesis, and the natural history of the disease.

Expert faculty in this CME Outfitters Live and On Demand will provide needed education about the evolving science of IBD to inform and improve treatment selection, manage side effects, and personalize the clinical approach. Faculty will address key goals to better identify patients who are likely to benefit from therapy, based on clinical criteria, but also on genotypic data.2


  1. Festen EA, Weersma RK. How will insights from genetics translate to clinical practice in inflammatory bowel disease? Best Pract Res Clin Gastroenterol. 2014;28(3):387-397. PMID: 24913379.
  2. D'Haens G, Bressler BL, Danese S, et al. Identified areas of need to enhance evidence-based inflammatory bowel disease management and patient care. Presented at: 19th Congress of ECCO; Copenhagen Denmark: February 20-22, 2014. Abstract DOP082.

Activity Goal

This educational activity centers on the CME Outfutters Make One Change Statement. This statement is crafted from pertinent quality measures or clinical guidelines as a performance challenge to all participants. The Make One Change Statement for this activity is:

Develop an individualized treatment plan that includes regular discussions of side effects and continuously evaluates for treatment failure in individuals with IBD.

Learning Objectives

At the end of this CE activity, participants should be able to:

  • Define the mechanism of disease of IBD and the role of novel agents in treatment choices.
  • Describe available treatment paradigms and options for treatment failure in moderate-to-severe IBD.
  • Implement a maintenance treatment plan for IBD to achieve mucosal healing and remission in patients with moderate-to-severe IBD.

The following learning objectives pertain only to those requesting CNE credit:

  • Define the mechanism of disease of IBD and the role of novel agents in treatment choices.
  • Review available treatment paradigms and options for treatment failure in moderate-to-severe IBD.
  • Evaluate a personalized treatment plan to maintain mucosal health and remission in patients with moderate-to-severe IBD.

Financial Support

Supported by an educational grant from Takeda Pharmaceuticals International, Inc., U.S. Region.

Target Audience

Gastroenterologists, physician assistants, nurse practitioners, nurses, pharmacists, and other health care professionals who manage and counsel patients with IBD.

Credit Information

CME Credit (Physicians):
CME Outfitters, LLC, is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

CME Outfitters, LLC, designates this enduring material for a maximum of 1.5 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

CNE Credit (Nurses):
Provider approved by the California Board of Registered Nursing, Provider Number CEP 15510, for 1.5 contact hours.

CPE Credit (Pharmacists):
ACPE CME Outfitters, LLC, is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education. 1.5 contact hours (0.15 CEUs)
Universal Activity Number: 0376-0000-15-005-L01-P (live programs)
0376-0000-15-005-H01-P (recorded programs)
Activity Type: knowledge-based

Post-tests, credit request forms, and activity evaluations must be completed online at www.cmeoutfitters.com/TST967 (requires free account activation). Participants should review the required information: target audience, learning objectives, and disclosure information. Participants should complete the entire self-study activity and print their certificate or statement of credit immediately (75% pass rate required). This website supports all browsers except Internet Explorer for Mac. For complete technical requirements and privacy policy, visit www.neurosciencecme.com/technical.asp.

Disclosure Declaration

It is the policy of CME Outfitters, LLC, to ensure independence, balance, objectivity, and scientific rigor and integrity in all of their CME/CE activities. Faculty must disclose to the participants any relationships with commercial companies whose products or devices may be mentioned in faculty presentations, or with the commercial supporter of this CME/CE activity. CME Outfitters, LLC, has evaluated, identified, and attempted to resolve any potential conflicts of interest through a rigorous content validation procedure, use of evidence-based data/research, and a multidisciplinary peer review process. The following information is for participant information only. It is not assumed that these relationships will have a negative impact on the presentations.

Dr. Cohen has disclosed that he has received research grants from Janssen Research & Development, LLC (Johnson & Johnson / Centocor). He serves as a consultant to AbbVie Inc.; Celgene Corporation; Entera Health, Inc.; Hospira, Inc.; Janssen Research & Development, LLC (Johnson & Johnson / Centocor); Prometheus Laboratories Inc.; Salix Pharmaceuticals, Inc.; Sandoz Biopharmaceuticals; Shire; Takeda Pharmaceuticals U.S.A., Inc.; and UCB, Inc. He is on the speakers bureau of AbbVie Inc.; Entera Health, Inc.; Salix Pharmaceuticals, Inc.; and Shire PLC.

Dr. Lichtenstein has disclosed that he has received research grants from Ferring Pharmaceuticals; Janssen Biotech, Inc./Centocor Ortho Biotech, Inc.; Prometheus Laboratories Inc.; Salix Pharmaceuticals, Inc.; Santarus, Inc.; Shire; UCB, Inc.; and Warner Chilcotte. He serves as a consultant for AbbVie Inc.; Actavis; Alaven Pharmaceutical LLC; Ferring Pharmaceuticals; Hospira; Janssen Biotech, Inc./Centocor Ortho Biotech, Inc.; Luitpold Pharmaceuticals, Inc./American Regent, Inc.; Pfizer Inc.; Prometheus Laboratories Inc.; Salix Pharmaceuticals, Inc.; Santarus, Inc.; Schering-Plough Corporation; Shire; Takeda Pharmaceuticals U.S.A., Inc.; UCB, Inc.; Warner Chilcotte. He has received other financial or material support as Editor, Clinical Advances in Gastroenterology; Editor, Gastroenterology & Hepatology; Ironwood (CME program); Luitpold Pharmaceuticals/American Regent, Inc. (CME); SLACK, Inc. (Book royalty)

Dr. Reguerio has disclosed that he serves as a consultant to AbbVie Inc.; Janssen Pharmaceuticals, Inc.; Shire; Takeda Pharmaceuticals U.S.A., Inc.; and UCB, Inc.

Jeffery Helfand, DO, MS (peer reviewer) has no disclosures to report.

Kimberley Murray, RN, MS (peer reviewer) has no disclosures to report.

Frances C. Daniel, MPH (planning committee) has no disclosures to report.

Sharon Tordoff, CCMEP (planning committee) has no disclosures to report.

Sandra Haas Binford, MAEd (planning committee) has no disclosures to report.

Disclosures have been obtained from CME Outfitters staff: No disclosures to report.

Unlabeled Use Disclosure

Faculty of this CME/CE activity may include discussions of products or devices that are not currently labeled for use by the FDA. The faculty have been informed of their responsibility to disclose to the audience if they will be discussing off-label or investigational uses (any uses not approved by the FDA) of products or devices.

CME Outfitters, LLC, the faculty, and Takeda Pharmaceuticals International, Inc., U.S. Region do not endorse the use of any product outside of the FDA labeled indications. Medical professionals should not utilize the procedures, products, or diagnosis techniques discussed during this activity without evaluation of their patient for contraindications or dangers of use.

Questions about this activity? Call us at 877.CME.PROS (877.263.7767).

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